Some Variables Which Influence the Activated Partial Thromboplastin Time Assay

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Some variables which influence the activated partial thromboplastin time assay.

‘ITHE partial thromboplastin time assay (PTT) as developed by Langdell et al. (1) has proved to be a very usef ul test for studying the coagulatioll mechanism silice it C 11 reveal tile al)SellCe of any factor except Factor VII and platelets. lnder rigorously cOlitrolled COll(litiOlIS, the reproducibility of tile test is satisfactory. However, any change ill tile surface of the svl’inge, test t...

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CONTEXT Elevated free hemoglobin (Hb) and bilirubinemia complicate extracorporeal membrane oxygenation and could affect unfractionated heparin (UH) therapy monitoring by anti-Xa assay and activated partial thromboplastin time (aPTT). OBJECTIVES To compare in vitro response of anti-Xa and aPTT assays to UH in samples with artificial hyperbilirubinemia and hyperhemoglobinemia and to estimate if...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 1966

ISSN: 0009-9147,1530-8561

DOI: 10.1093/clinchem/12.5.269